প্রথমেই একটু থিওরি জানা দরকার। কোভিড ১৯-এর কারণে ভাইরোলজি সম্পর্কে সাধারণ মানুষের জ্ঞান আগের থেকে কিছুটা হলেও বেড়েছে। নানা জায়গায় নিশ্চয়ই করোনা ভাইরাসের বহুরূপী অনেক ‘স্ট্রেইন’-এর নাম শুনেছেন অনেকে। ফ্লু ভাইরাস বা ইনফ্লুয়েঞ্জা ভাইরাসেরও এমন অনেক স্ট্রেইন ও টাইপ/ সাব-টাইপ রয়েছে।
প্রথমেই ফ্লু ভাইরাসের এই জাত-উপজাতগুলো সম্পর্কে জেনে নয়া যাক। A, B, C এবং D; এই চার টাইপের ইনফ্লুয়েঞ্জা ভাইরাস পাওয়া যায়। এর মধ্যে ইনফ্লুয়েঞ্জা A ও B হিউম্যান ফ্লু এর জন্য দায়ী। আর, শুধুমাত্র A টাইপ ইনফ্লুয়েঞ্জাই শীতকালীন ফ্লু প্যান্ডেমিকগুলোর পিছনের মূল হোতা।
Influenza A ভাইরাসগুলোকেও তাদের সারফেস প্রোটিনের বিভিন্নতা অনুযায়ী নানা সাবটাইপে ভাগ করা হয়। প্রোটিনগুলো হলো হেমাগ্লুটোনিন (H) ও নিউরামিনিডেজ (N)। যেমন ধরুন, হেমাগ্লুটোনিন সাবটাইপ 3 ও নিউরামিনিডেজ সাবটাইপ 2 বিশিষ্ট ভাইরাসটিকে আমরা বলব H3N2। এদেরকেও পরবর্তীতে আরো নানা টাইপ/ সাবটাইপে ভাগ করা যায়। অপরদিকে ইনফ্লুয়েঞ্জা B ভাইরাসের কোনো সাবটাইপ না থাকলেও B/Victoria ও B/Yamagata নামে দুটি লাইনেজে এদের বিভক্ত করা যায়।
এবার আসি কেন এরা “সম্ভবত বিলুপ্ত” হলো। যে কেউই হয়তো গেস করতে পারছেন, কোভিড ১৯ মহামারীর ফলে নেয়া সুরক্ষা ব্যবস্থা সমূহ যেমন, মাস্ক পরিধান, বার বার সাবান দিয়ে হাত ধোয়া এবং লকডাউনের পাশাপাশি শিক্ষা প্রতিষ্ঠান ও অন্যান্য পাবলিক গ্যাদারিং বন্ধ রাখা ইত্যাদি ফ্লুএ বিরুদ্ধে এযাত্রা আমাদের বেশ কয়েক ধাপ এগিয়ে রাখল। কারণ অতি সাধারণ, ফ্লু ও করোনা ভাইরাস মোটামুটি সেইম প্রসিজিউরে সংক্রমণ ঘটায়।
লকডাউন যুগের শুরু থেকেই ফ্লুর সংক্রমণ খুবই উচ্চ হারে হ্রাস পাচ্ছিল। ২০-২১ ফ্লু সিজনে তেমন কোনো সংক্রমণই হয়নি ধরা যায়। গবেষকরা ধারণা করছেন, H3N2 সাবটাইপের স্ট্রেইনগুলোর একটা বড়ো অংশ ও B/Yamagata সম্পূর্ণ বিলুপ্ত হয়ে গেছে। ফ্লু মনিটরিং-য়ের গ্লোবাল ডাটাবেইজে এই দুটোর কোনো তথ্য গত এক বছরে অন্তর্ভূক্ত করা হয়নি! অর্থাৎ, এই দুটো দ্বারা সারা বিশ্বে গত বছরে প্র্যাকটিক্যালি কেউ সংক্রমিত হয়নি, যেটা অবশ্যই খুব আশাব্যঞ্জক খবর।
এবার সার্বিক পরিস্থিতিটা একটু বিশ্লেষণ করা যাক–
প্রথমত, গ্লোবাল ডাটাবেইজে ভাইরাসদ্বয়ের কোনো এন্ট্রি আসে নাই মানে এই না পৃথিবী থেকে এরা আসলেই সম্পূর্ন বিলুপ্ত হয়ে গেছে। হয়তো এখনো থার্ড ওয়ার্ল্ড কান্ট্রিগুলোর কোনো একটায় ঘাপটি মেরে বসে আছে এবং (কোভিডের কারণে) সে দেশের বিপদগ্রস্থ স্বাস্থব্যবস্থা এবছর ফ্লুর পিছনে টাইম দিতে চায়নি। এটা আমাদের মানতেই হবে কোভিড ১৯ এর কারনেও পুরো বিশ্বেই স্বাস্থব্যবস্থা যে কত বড় একটা ঝাঁকুনি খেয়েছে এবং বিশ্বব্যাপী ফ্লু এর সঠিক মনিটরিং নিয়েও তাহলে যথেষ্ঠ প্রশ্ন থেকে যায়।
ফ্লুয়ের ওই স্ট্রেইন দুটো বিলুপ্ত হলে আমাদের কী লাভ হবে? ব্যাখ্যা করছি–
ইনফ্লুয়েঞ্জা ভাইরাসের গোত্রটা বেশ প্যারাদায়ক। এদের মাঝে অনেক ডাইভারসেটি। তার উপর দিন দিন এদের মাঝে জেনেটিক দূরত্ব বেড়েই চলছে। যত বেশি বৈচিত্র্য, তত আমাদের জন্য সমস্যা। সার্বজনীন একটা ফ্লু ভ্যাক্সিন কবে নাগাদ সব রকম ফ্লু থেকে আমাদের আর নিরাপদ রাখতে পারবে না, তার আর বলা যাচ্ছে না। তবে খুব শীঘ্রই সেদিন আসবে ধারণা করা হচ্ছিল। বর্তমানের ফ্লু ভ্যাক্সিনগুলোয় অলরেডি ৪টা পার্ট থাকে প্রতিটি যথাক্রমে H1N1 A, H3N2 A, B/Victoria ও B/Yamagata-র জন্য। কিন্তু কিছুদিন আগেও B/Yamagata-র জন্য কোনো ভ্যাক্সিন আমাদের দিতে হতো না। এই চারটা ভ্যাক্সিনকে একটা সিঙ্গেল ডোজে আনতে অনেক সমস্যা পোহাতে হয়। মূলকথা হলো, ইনফ্লুয়েঞ্জা ভাইরাসের এই ডাইভারসিটি আমাদের রীতিমতো ঘাম ঝড়িয়ে ছাড়ছে।
এই যখন অবস্থা, B/Yamagata এবং H3N2 এর একাধিক ক্ল্যাডের সম্ভাব্য বিলুপ্তির খবর অবশ্যই সেলিব্রেট করার মতন।
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