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দলটি কম্পিউটার মডেলিং এর সহায়তায় ভার্চুয়াল স্ক্রিনিং (ভার্চুয়াল স্ক্রিনিং বা ভিএস হলো একটা কম্পুটেশনাল পদ্ধতি যা ঔষধ আবিস্কারে ব্যবহৃত হয়) এর মাধ্যমে ২০০০ ঔষধের মধ্যে এমন ২০০ টি ঔষধ শনাক্ত করে যারা কোভিড মোকাবিলায় ইফেক্টিভ হতে পারে। সবচেয়ে এক্সাইটিং ব্যাপার হলো এই ২০০ ঔষধের মধ্যে ৪০টি ইতোমধ্যে ক্লিনিক্যাল ট্রায়ালে আছে যা এই দলটির গবেষণা এবং তার ফলাফলের সফলতা নিশ্চিত করে।
আরো পড়ুন: সুপার কোষের মাধ্যমে এন্টিবডির হাত থেকে পালিয়ে থাকছে করোনা ভাইরাস!
গবেষকেরা ভাইরাল ইনফেকশনে ব্যবহৃত ঐসব ঔষধ এর একটি সাবসেট পরীক্ষা করে দুইটি
ঔষধ (একটি এন্টিম্যালেরিয়াল ঔষধ, অন্যটি রিউমাটয়েড আর্থ্রাইটিসের চিকিৎসায় ব্যবহৃত হয়) শনাক্ত করেন যেগুলো করোনা দমন করতে সক্ষম হয়। এটি গবেষণার সফলতা আরো জোড়ালো ভাবে প্রমাণ করতে সক্ষম হয়।
গবেষণার নেতৃত্ব প্রদানকারী এবং মিলনার থেরাপিউটিক্স ইনস্টিটিউটের পরিচালক অধ্যাপক টনি কাউজারাইডস বলেন যে, “এটি ভাইরাসটির বিরুদ্ধে লড়াইয়ের জন্য আমাদের অস্ত্রাগারে আরও অনেকগুলি অস্ত্র দিতে পারে”
মিলনার থেরাপিউটিক্স ইনস্টিটিউটের পরিসংখ্যা নির্ভর গবেষণা ও এআই প্রধান ড. নামশিক হান বলেন যে, ” আমাদের গবেষণা কোভিডের আন্ডারলায়িং মেকানিজম সম্পর্কে আমাদের অভাবনীয় তথ্য দিয়েছে এবং আমাদের অনেক আশাপ্রদ ঔষধের সন্ধান দিয়েছে যা করোনা ভাইরাস চিকিৎসায় বা প্রতিরোধে ব্যবহার করা যাবে।“
গবেষণাপত্রটি ৩০শে জুন, ২০২১ এ Science Advances.জার্নালে প্রকাশিত হয়।
গবেষণা পত্র: Identification of SARS-CoV-2–induced pathways reveals drug repurposing strategies, Science Advances (2021)
তথ্যসূত্র: কেমব্রিজ বিশ্ববিদ্যালয়
Should we take Ivermectin for prophylaxis ?
বলা হচ্ছে বেশ কার্যকরী। তবে বিশেষজ্ঞের পরামর্শ অনুযায়ী পদক্ষেপ নেয়া উচিৎ।
পেপার: https://doi.org/10.24018/ejmed.2020.2.6.599
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