চিকিৎসাবিজ্ঞানে নোবেল পুরষ্কার ২০২১

২০২১ সালের চিকিৎসাবিজ্ঞান (ফিজিওলজি বা মেডিসিনে) এ যৌথভাবে নোবেল পুরস্কার পেলেন ডেভিড জুলিয়াস এবং আরডেম পাটাপুটিয়ান। তাদের গবেষণার বিষয় ছিল "তাপমাত্রা এবং স্পর্শের জন্য দ্বায়ী রিসেপ্টর" এর আবিষ্কার।

কারোলিন্সকা ইনস্টিটিউটে নোবেল পরিষদ (Nobel Assembly at the Karolinska Institute) ২০২১ সালের চিকিৎসাবিজ্ঞান (ফিজিওলজি বা মেডিসিন)-এ নোবেল পুরস্কার যৌথভাবে ডেভিড জুলিয়াস এবং আরডেম পাটাপুটিয়ানকে দেওয়ার ঘোষণা করা হয়। তাদের গবেষণার বিষয় ছিল “তাপমাত্রা এবং স্পর্শের জন্য দ্বায়ী রিসেপ্টর” এর আবিষ্কার।

আমাদের গরম, ঠান্ডা এবং স্পর্শ অনুভব করার ক্ষমতা বেঁচে থাকার জন্য একটি অপরিহার্য প্রক্রিয়া। আমাদের চারিদিকের পরিবেশ সেই অনুভূতিকে আরও সজাগ করে তোলে, যেটা পৃথিবীতে টিকে থাকার ক্ষেত্রে প্রতিমুহূর্তে সহায়তা করে। আমাদের দৈনন্দিন জীবনে আমরা এই অনুভূতিগুলিকে স্বাভাবিকভাবেই গ্রহণ করি। কিন্তু প্রশ্ন থেকেই যায় যে কীভাবে আমাদের স্নায়ুতে এসকল তাপমাত্রা এবং চাপ অনুভূত হয়? এই বছরের নোবেল পুরস্কার বিজয়ীরা এই প্রশ্নের সমাধান করেছেন।

এই কাজে ডেভিড জুলিয়াস তার গবেষণায় ব্যবহার করেছিলেন Capsaicin (C18H27NO3) যেটি মুলত মরিচে পাওয়া যায়। এই যৌগিক পদার্থ মরিচের জ্বলার অনুভূতি জাগায়। তিনি এই অনুভূতির জন্য দ্বায়ী ত্বকের স্নায়ু প্রান্তের একটি সেন্সর সনাক্ত করেন, যা জ্বলার প্রতিক্রিয়া সৃষ্টি করে। এদিকে আরডেম পাটাপুটিয়ান চাপ-সংবেদনশীল কোষ ব্যবহার করে একটি নতুন ধরনের সেন্সর আবিষ্কার করে যা ত্বক এবং অভ্যন্তরীণ অঙ্গগুলির মেকানিকাল উদ্দীপনায় সাড়া দেয়। এই যুগান্তকারী আবিষ্কারসমূহ নতুন বহু গবেষণার শুরুতে সহায়তা করেছে। যার ফলে আমাদের স্নায়ুতন্ত্র কীভাবে তাপ, ঠান্ডা এবং মেকানিকাল উদ্দীপনা অনুভব করে তা আমাদের বুঝতে সাহায্য করবে।

David Julius used capsaicin from chili peppers to identify TRPV1, an ion channel activated by painful heat. Additional related ion channels were identified and we now understand how different temperatures can induce electrical signals in the nervous system. C’ est la que le traitement des problemes asgg.fr/ d’ erection venir.
Patapoutian used cultured mechanosensitive cells to identify an ion
channel activated by mechanical force. After painstaking work, Piezo1 was
identified. Based on its similarity to Piezo1, a second ion channel was found
(Piezo2).

এবারের নোবেল বিজয়ীদের আবিষ্কার চিকিৎসাবিজ্ঞানে যুগান্তকারী প্রভাব ফেলতে পারে। তাদের আবিষ্কার আমাদের বুঝতে সাহায্য করেছেন যে কীভাবে তাপ, ঠান্ডা এবং মেকানিকাল শক্তি স্নায়ু আবেগের সূচনা করতে পারে যা আমাদের চারপাশের জগৎকে উপলব্ধি করতে এবং মানিয়ে নিতে দেয়। এসব আবিষ্কার বিভিন্ন শারীরবৃত্তীয় প্রক্রিয়ায় তাদের কার্যাবলী ব্যাখ্যা করার ক্ষেত্রে সাহায্য করবে। গবেষণার জ্ঞান দীর্ঘস্থায়ী ব্যথা সহ বিস্তৃত অবস্থার বিভিন্ন রোগের চিকিৎসা বিকাশের জন্য ব্যবহৃত হবে।

Source: NobelPrize.org
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